Current legal intervention regarding "experimental" treatments must be changed: an analysis of high doses of chemotherapy with autologous bone marrow transplantation for breast cancer patients.
نویسنده
چکیده
منابع مشابه
AUTOLOGOUS MARROW TRANSPLANTATION IN THE TREATMENT OF MOPP AND ABVD-RESI STANT HODGKIN\'S DISEASE
Six patients with disseminated Hodgkin's disease resistant to MOPP (mechlorethamine, vincristine, procarbazine and prednisolone), and ABVD (adriamycin, bleomycin, vinblastine and dacarbazine) chemotherapy were treated with high-dose chemotherapy and autologous marrow transplantation. The patients first underwent marrow aspiration and storage for subsequent autologous bone marrow transplant...
متن کاملWhat Is the Role of High-dose Chemotherapy and Autologous Marrow Support for Patients With Breast Cancer?
I will first focus on the use of high-dose chemotherapy regimens in metastatic breast cancer. With that background, we will be better able to evaluate the adjuvant use of high-dose therapy in the primary disease or adjuvant setting. We have fairly large amounts of data in metastatic disease, though only one randomized clinical trial is completed and published. Outcomes have not changed dramatic...
متن کاملEvaluating promising new treatments for life-threatening disease: implications of the HDC/ABMT experience for treating breast cancer.
threatening diseases often inspire hope, patient demand, and physician enthusiasm before evaluation. In the late 1980s, highdose chemotherapy/autologous bone marrow transplantation (HDC/ABMT) emerged as a promising medical procedure for treating metastatic and high-risk breast cancer. But procedures, unlike new drugs, face no requirement for evaluation by randomized clinical trials (RCTs). In t...
متن کاملFertility preservation for patients with hematologic malignancies: The Korean Society for Fertility Preservation clinical guidelines
Although the survival rate of hematologic malignancies in young patients is very high, cytotoxic therapies such as chemotherapy and total body irradiation therapy can significantly reduce a patient's reproductive capacity and cause irreversible infertility. Early ovarian failure also commonly occurs following additional cancer treatment, bone marrow transplantation, or autologous transplantatio...
متن کاملConventional-dose chemotherapy compared with high-dose chemotherapy plus autologous hematopoietic stem-cell transplantation for metastatic breast cancer. Philadelphia Bone Marrow Transplant Group.
BACKGROUND We conducted a randomized trial in which we compared high-dose chemotherapy plus hematopoietic stem-cell rescue with a prolonged course of monthly conventional-dose chemotherapy in women with metastatic breast cancer. METHODS Women 18 to 60 years of age who had metastatic breast cancer received four to six cycles of standard combination chemotherapy. Patients who had a complete or ...
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ورودعنوان ژورنال:
- Journal of law and health
دوره 13 2 شماره
صفحات -
تاریخ انتشار 1998